age- and sex-specific prevalence and ten-year risk for cardiovascular disease of all 16 risk factor combinations of the metabolic syndrome - a cross-sectional study年龄和性别患病率和十年的心血管疾病风险的所有16个风险因素组合代谢综合症u2014u2014一个横断面研究.pdfVIP

Moebus et al. Cardiovascular Diabetology 2010, 9:34 CARDIO /content/9/1/34 VASCULAR DIABETOLOGY ORIGINAL INVESTIGATION Open Access Age- and sex-specific prevalence and ten-year risk for cardiovascular disease of all 16 risk factor combinations of the metabolic syndrome - A cross-sectional study 1* 1 1 1 2 3 Susanne Moebus , Chakrapani Balijepalli , Christian Lösch , Laura Göres , Bernd von Stritzky , Peter Bramlage , 4 1 Jürgen Wasem , Karl-Heinz Jöckel Abstract Background: Based on the AHA/NHLBI-definition three out of five cardiometabolic traits must be present for the diagnosis of the metabolic syndrome (MetS), resulting in 16 different combination types. The associated cardiovascular risk may however be different and specific combination may be indicative of an increased risk, furthermore little is known to which extent these 16 combinations contribute to the overall prevalence of MetS. Here we assessed the prevalence of all 16 combination types of MetS, analyzed the impact of age and gender on prevalence rates, and estimated the 10-year risk of fatal and non-fatal myocardial infarction (MI) of each MetS combination type. Methods: We used data of the German Metabolic and Cardiovascular Risk Project (GEMCAS), a cross-sectional study, performed during October 2005, including 35,869 participants (aged 18-99 years, 61% women). Age- standardized prevalence and 10-year PROCAM and ESC risk scores for