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aged garlic extract therapy for sickle cell anemia patients陈大蒜汁治疗镰状细胞性贫血的病人
BMC Blood Disorders BioMed Central
BMC Blood Disorders x
2002,
2
Research article
Aged garlic extract therapy for sickle cell anemia patients
Junichiro Takasu 1, Rolando Uykimpang 1, Maria Alenor Sunga 1,
Harunobu Amagase 2 and Yutaka Niihara * 1
Address: 1Department of Medicine, Harbor-UCLA Medical Center, UCLA School of Medicine, Torrance, CA and 2Wakunaga of America Co., Ltd.,
Mission Viejo, CA
E-mail: Junichiro Takasu - jtakasu@; Rolando Uykimpang - yniihara@; Maria Sunga - yniihara@;
Harunobu Amagase - yniihara@; Yutaka Niihara* - yniihara@
*Corresponding author
Published: 19 June 2002 Received: 15 April 2002
Accepted: 19 June 2002
BMC Blood Disorders 2002, 2:3
This article is available from: /1471-2326/2/3
© 2002 Takasu et al; licensee BioMed Central Ltd. Verbatim copying and redistribution of this article are permitted in any medium for any purpose, provided
this notice is preserved along with the articles original URL.
Abstract
Background: Sickle cell anemia is one of the most prevalent hereditary disorders with prominent
morbidity and mortality. With this disorder oxidative, phenomena play a significant role in its
pathophysiology. One of the garlic (Allium sativum L.) formulations, aged garlic extract (AGE), has
been reported to exert an anti-oxidant effect in vitro, we have evaluated the anti-oxidant effect of
AGE on sickle red blood cells (RBC).
Methods: Five patients (two men and three women, mean age 40 ± 15 years, range 24–58 years)
with sickle cell anemia participated in the
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