alcohol consumption and breast cancer risk饮酒和乳腺癌的风险.pdfVIP

Available online /supplements/11/S3/S3 Short communication Alcohol consumption and breast cancer risk Peter Boyle and Paolo Boffetta International Prevention Research Institute, 95 cours Lafayette, 69006 Lyon, France Corresponding author: Peter Boyle, peter.boyle@ Published: 18 December 2009 Breast Cancer Research 2009, 11(Suppl 3):S3 This article is online at (doi:10.1186/bcr2422) /supplements/11/S3/S3 © 2009 BioMed Central Ltd Introduction During the first 4 years of follow-up, 601 cases of breast Alcohol consumption has been associated with a variety of cancer were diagnosed among cohort members [4]. different forms of cancer in man for several centuries. The evidence linking alcohol drinking to cancer risk has been Among women who consumed 5 to 14 g alcohol daily (about reviewed recently [1-3]. There is convincing epidemiological three to nine drinks per week), the age-adjusted relative risk evidence that the consumption of alcoholic beverages of breast cancer reported was 1.3 (95% confidence interval increases the risk of cancers of the oral cavity, the pharynx (CI), 1.1 to 1.7). Consumption of 15 g alcohol or more per and the larynx, and the risk of squamous cell carcinoma of the day was associated with a relative risk of 1.6 (95% CI, 1.3 to oesophagus. The risks tend to increase with the amount of 2.0) and there was evidence of a highly significant increase in ethanol drunk, in the absence of any clearly defined threshold risk wit