analyses of zebrafish and xenopus oocyte maturation reveal conserved and diverged features of translational regulation of maternal cyclin b1 mrna分析斑马鱼和非洲爪蟾蜍卵母细胞成熟揭示守恒和分化特性转化监管的孕产妇细胞周期蛋白b1 mrna.pdfVIP

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analyses of zebrafish and xenopus oocyte maturation reveal conserved and diverged features of translational regulation of maternal cyclin b1 mrna分析斑马鱼和非洲爪蟾蜍卵母细胞成熟揭示守恒和分化特性转化监管的孕产妇细胞周期蛋白b1 mrna.pdf

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analyses of zebrafish and xenopus oocyte maturation reveal conserved and diverged features of translational regulation of maternal cyclin b1 mrna分析斑马鱼和非洲爪蟾蜍卵母细胞成熟揭示守恒和分化特性转化监管的孕产妇细胞周期蛋白b1 mrna

BMC Developmental Biology BioMed Central Research article Open Access Analyses of zebrafish and Xenopus oocyte maturation reveal conserved and diverged features of translational regulation of maternal cyclin B1 mRNA Yan Zhang and Michael D Sheets* Address: University of Wisconsin School of Medicine and Public Health, Department of Biomolecular Chemistry, 1300 University Avenue Madison, Madison, Wisconsin 53706, USA Email: Yan Zhang - zhang7@; Michael D Sheets* - mdsheets@ * Corresponding author Published: 28 January 2009 Received: 19 June 2008 Accepted: 28 January 2009 BMC Developmental Biology 2009, 9:7 doi:10.1186/1471-213X-9-7 This article is available from: /1471-213X/9/7 © 2009 Zhang and Sheets; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Vertebrate development relies on the regulated translation of stored maternal mRNAs, but how these regulatory mechanisms may have evolved to control translational efficiency of individual mRNAs is poorly understood. We compared the translational regulation and polyadenylation of the cyclin B1 mRNA during zebrafish and Xenopus oocyte maturation. Polyadenylation and translational activation of cyclin B1 mRNA is well characterized durin