原创力文档analysis of egfr, her2, and top2a gene status and chromosomal polysomy in gastric adenocarcinoma from chinese patients分析表皮生长因子受体、her2和top2a基因状态和从中国胃腺癌患者的染色体多体性.pdfVIP
- 1、本文档共12页，可阅读全部内容。
- 2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
- 3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
analysis of egfr, her2, and top2a gene status and chromosomal polysomy in gastric adenocarcinoma from chinese patients分析表皮生长因子受体、her2和top2a基因状态和从中国胃腺癌患者的染色体多体性
BMC Cancer BioMed Central
Research article Open Access
Analysis of EGFR, HER2, and TOP2A gene status and chromosomal
polysomy in gastric adenocarcinoma from Chinese patients
Zhiyong Liang, Xuan Zeng, Jie Gao, Shafei Wu, Peng Wang, Xiaohua Shi,
Jing Zhang and Tonghua Liu*
Address: Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, PR China
Email: Zhiyong Liang - liangzhiyong1220@; Xuan Zeng - zengx88@; Jie Gao - zy_795@;
Shafei Wu - Suphie@; Peng Wang - chinaroc@; Xiaohua Shi - shixiaohua3762@;
Jing Zhang - jingzhangsmile@163.com; Tonghua Liu* - liuth_pumch@
* Corresponding author
Published: 6 December 2008 Received: 29 March 2008
Accepted: 6 December 2008
BMC Cancer 2008, 8:363 doi:10.1186/1471-2407-8-363
This article is available from: /1471-2407/8/363
© 2008 Liang et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The EGFR and HER2 genes are located on chromosomes 7 and 17, respectively. They are
therapeutic targets in some tumors. The TOP2A gene, which is located near HER2 on chromosome 17,
is the target of many chemotherapeutic agents, and co-amplification of HER2 and TOP2A has been
described in several tumor types. Herein, we investigated the gene status of EGFR, HER2, and TOP2A in
您可能关注的文档
- an initial map of chromosomal segmental copy number variations in the chicken染色体节段的初始映射拷贝数变化的鸡.pdf
- an inpatient rehabilitation model of care targeting patients with cognitive impairment住院病人康复的护理模式针对患者认知障碍.pdf
- an informatics supported web-based data annotation and query tool to expedite translational research for head and neck malignancies一个信息支持网络数据注释和查询工具加快转化研究头颈部恶性肿瘤.pdf
- an insight into the phylogenetic history of hox linked gene families in vertebrates系统发育的历史有了深入的了解hox基因家族在脊椎动物有关.pdf
- an insight into the suspected hba2' cases detected by high performance liquid chromatography in pakistan一个洞察hba2嫌疑的情况下检测到巴基斯坦的高效液相色谱法.pdf
- an in silico study of the molecular basis of b-raf activation and conformational stability的在网上研究b - raf激活的分子基础和构象稳定.pdf
- an institutional perspective on the impact of recent antibiotic exposure on length of stay and hospital costs for patients with gram-negative sepsis制度视角的影响,近期抗生素暴露在停留时间和医院的革兰氏阴性脓毒症患者的成本.pdf
- an initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, cop1最初的生物化学和细胞生物学特性的哺乳动物同系物中央发育开关,cop1.pdf
- an instrument assessing patient satisfaction with day care in hospitals乐器评估病人在医院满意度日托.pdf
- an insight into the sialome of the oriental rat flea, xenopsylla cheopis (rots)东方的洞察sialome老鼠跳蚤,xenopsylla cheopis(腐烂).pdf
- analysis of folylpoly-γ-glutamate synthetase gene expression in human b-precursor all and t-lineage all cells分析folylpoly-γ-glutamate合成酶基因表达在人类b-precursor和t-lineage所有细胞.pdf
- analysis of frailty and survival from late middle age in the beijing longitudinal study of aging脆弱和生存分析北京中年后期的衰老的纵向研究.pdf
- analysis of free energy signals arising from nucleotide hybridization between rrna and mrna sequences during translation in eubacteria自由能的分析信号由核苷酸之间的杂交rrna和信使rna序列在翻译真细菌.pdf
- analysis of gene mutations associated with isoniazid, rifampicin and ethambutol resistance among mycobacterium tuberculosis isolates from ethiopia分析基因突变与异烟肼、利福平、乙胺丁醇结核分枝杆菌分离株之间的阻力来自埃塞俄比亚.pdf
- analysis of gene order data supports vertical inheritance of the leukotoxin operon and genome rearrangements in the 5' flanking region in genus mannheimia分析基因顺序的数据支持垂直继承白细胞毒素操纵子和基因重组5u2019侧翼地区属mannheimia.pdf
- analysis of gene expression patterns by microarray hybridization in blood mononuclear cells of sla-drb1 defined canadian yorkshire pigs分析基因表达微阵列杂交模式的血液单核细胞sla-drb1定义的加拿大约克夏猪.pdf
- analysis of genetic diversity in brown swiss, jersey and holstein populations using genome-wide single nucleotide polymorphism markers分析遗传多样性在棕色的瑞士,球衣和荷斯坦人口使用全基因组单核苷酸多态性标记.pdf
- analysis of genetic heterogeneity in the hcar adenovirus-binding ig1 domain in a caucasian flemish population分析遗传异质性的hcar adenovirus-binding ig1域在高加索佛兰德的人口.pdf
- analysis of genomic differences among clostridium botulinum type a1 strains分析基因组差异肉毒梭状芽胞杆菌a1型菌株.pdf
- analysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection分析基因表达在前列腺癌上皮和间质基质细胞使用激光捕获显微解剖.pdf
文档评论（0）