antibiotics for the primary prevention of acute rheumatic fever a meta-analysis抗生素的初级预防急性风湿热荟萃分析.pdfVIP

BMC Cardiovascular Disorders BioMed Central Research article Open Access Antibiotics for the primary prevention of acute rheumatic fever: a meta-analysis 1,2 1 2 Katharine A Robertson , Jimmy A Volmink and Bongani M Mayosi* Address: 1Primary Health Care Directorate, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa and 2The Cardiac Clinic, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa Email: Katharine A Robertson - kate.robertson@; Jimmy A Volmink - jvolmink@cormack.uct.ac.za; Bongani M Mayosi* - bmayosi@uctgsh1.uct.ac.za * Corresponding author Published: 31 May 2005 Received: 22 August 2004 Accepted: 31 May 2005 BMC Cardiovascular Disorders 2005, 5:11 doi:10.1186/1471-2261-5-11 This article is available from: /1471-2261/5/11 © 2005 Robertson et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Rheumatic fever continues to put a significant burden on the health of low socio- economic populations in low and middle-income countries despite the near disappearance of the disease in the developed world over the past century. Antibiotics have long been thought