antimicrobial drugs for persistent diarrhoea of unknown or non-specific cause in children under six in low and middle income countries systematic review of randomized controlled trials抗菌药物持续腹泻6岁以下儿童的未知或非特异性造成低收入和中等收入国家随机对照试验的系统评价.pdfVIP

BMC Infectious Diseases BioMed Central Research article Open Access Antimicrobial drugs for persistent diarrhoea of unknown or non-specific cause in children under six in low and middle income countries: systematic review of randomized controlled trials Katharine Abba*, Rebecca Sinfield, C Anthony Hart and Paul Garner Address: Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK Email: Katharine Abba* - K.abba@liverpool.ac.uk; Rebecca Sinfield - Becca.sinfield@; Paul Garner - pgarner@liverpool.ac.uk * Corresponding author Published: 3 March 2009 Received: 19 August 2008 Accepted: 3 March 2009 BMC Infectious Diseases 2009, 9:24 doi:10.1186/1471-2334-9-24 This article is available from: /1471-2334/9/24 © 2009 Abba et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: A high proportion of children with persistent diarrhoea in middle and low income countries die. The best treatment is not clear. We conducted a systematic review to evaluate the effectiveness of antimicrobial drug treatment for persistent diarrhoea of unknown or non-specific cause. Methods: We included randomized comparisons of antimicrobial drugs for the treatment of persistent diarrhoea of unknown or non-specific cause in children under the