application of the multicellular tumour spheroid model to screen pet tracers for analysis of early response of chemotherapy in breast cancer肿瘤多细胞球体模型的应用程序屏幕pet示踪剂分析化疗在乳腺癌的早期反应.pdfVIP

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application of the multicellular tumour spheroid model to screen pet tracers for analysis of early response of chemotherapy in breast cancer肿瘤多细胞球体模型的应用程序屏幕pet示踪剂分析化疗在乳腺癌的早期反应.pdf

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application of the multicellular tumour spheroid model to screen pet tracers for analysis of early response of chemotherapy in breast cancer肿瘤多细胞球体模型的应用程序屏幕pet示踪剂分析化疗在乳腺癌的早期反应

Available online /content/9/4/R45 Vol 9 No 4 Open Access Research article Application of the multicellular tumour spheroid model to screen PET tracers for analysis of early response of chemotherapy in breast cancer 1,2 3 1 4 2 Azita Monazzam , Raymond Josephsson , Carl Blomqvist , Jörgen Carlsson , Bengt Långström and Mats Bergström3,5 1Institute of Oncology, Institute of Oncology, Radiology and Clinical Immunology, Uppsala University Hospital, SE-751 85 Uppsala, Sweden 2Uppsala Imanet, GE Healthcare (PET Center), SE-751 09, Uppsala, Sweden 3Clinical Imaging, Novartis Pharma, CH-4002, Basel, Switzerland 4Department of Biomedical Radiation Sciences, Institute of Oncology, Radiology and Clinical Immunology, Uppsala University Hospital, SE-751 85 Uppsala, Sweden 5Department of Pharmaceutical Biosciences, Uppsala University, SE-751 24, Uppsala, Sweden Corresponding author: Azita Monazzam, azita.monazzam@uppsala.imanet.se Received: 12 Apr 2007 Revisions requested: 21 May 2007 Revisions received: 26 Jun 2007 Accepted: 22 Jul 2007 Published: 22 Jul 2007 Breast Cancer Research 2007, 9:R45 (doi:10.1186/bcr1747) This article is online at: /content/9/4/R45 © 2007 Monazzam et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Positron emission tomography (PET) is suggested volume of the MTS at the end of the drug exposures, and