association of circulating chlamydia pneumoniae dna with cardiovascular disease a systematic review流通协会肺炎衣原体dna与心血管疾病系统回顾.pdfVIP

BMC Infectious Diseases BioMed Central BMC Infectious Diseases x 2002, Open Access 2 Research article Association of circulating Chlamydia pneumoniae DNA with cardiovascular disease: a systematic review 1,2 1 1 3 Marek Smieja* , James Mahony , Astrid Petrich , Jens Boman and Max Chernesky1 Address: 1Dept. of Pathology and Molecular Medicine, McMaster University, Hamilton ON, Canada, 2Dept. of Medicine, McMaster University, Hamilton ON, Canada and 3Dept. of Virology, Umea University, Umea, Sweden E-mail: Marek Smieja* - smiejam@mcmaster.ca; James Mahony - mahonyj@mcmaster.ca; Astrid Petrich - petricha@mcmaster.ca; Jens Boman - jens.boman@climi.umu.se; Max Chernesky - chernesk@mcmaster.ca *Corresponding author Published: 1 October 2002 Received: 9 July 2002 Accepted: 1 October 2002 BMC Infectious Diseases 2002, 2:21 This article is available from: /1471-2334/2/21 © 2002 Smieja et al; licensee BioMed Central Ltd. This article is published in Open Access: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: Chlamydia pneumoniae antigens, nucleic acids, or intact organisms have been detected in human atheroma. However, the presence of antibody does not predict subsequent cardiovascular (CV) events. We performed a system