automated migration analysis based on cell texture method reliability自动迁移分析基于细胞结构方法和可靠性.pdfVIP

BMC Cell Biology BioMed Central Software Open Access Automated migration analysis based on cell texture: method reliability †1,2 3,4 2 Jianfeng Qin , Thomas W Chittenden , Ling Gao and Justin D Pearlman*†1,2 1 2 Address: Thayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA, Dartmouth Advanced Imaging Center, Dartmouth- Hitchcock Medical Center, One Medical Drive, Lebanon, NH, 03756, USA, 3Angiogenesis Research Center, Dartmouth-Hitchcock Medical Center, One Medical Drive, Lebanon, NH, 03756, USA and 4Dartmouth Medical School, Hanover, NH, 03755, USA Email: Jianfeng Qin - Jianfeng.Qin@Dartmouth.EDU; Thomas W Chittenden - Thomas.W.Chittenden@Dartmouth.EDU; Ling Gao - Ling.Gao@; Justin D Pearlman* - Justin.D.Pearlman@Dartmouth.EDU * Corresponding author †Equal contributors Published: 03 March 2005 Received: 07 September 2004 Accepted: 03 March 2005 BMC Cell Biology 2005, 6:9 doi:10.1186/1471-2121-6-9 This article is available from: /1471-2121/6/9 © 2005 Qin et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: In this paper, we present and validate a way to measure a