insulin use, prescription patterns, regimens and costs.-a narrative from a developing country胰岛素、处方模式、方案和成本。.pdfVIP

Ogbera and Kuku Diabetology Metabolic Syndrome 2012, 4:50 DIABETOLOGY /content/4/1/50 METABOLIC SYNDROME RESEARCH Open Access Insulin use, prescription patterns, regimens and costs.-a narrative from a developing country Anthonia O Ogbera1* and Sonny F Kuku2 Abstract Background: Achieving good glycemic control is of paramount importance in the reduction of diabetes mellitus (DM) associated morbidity and mortality. Insulin plays a key role in the management of DM but unfortunately whilst some healthcare providers present insulin as a treatment of last resort , patients on insulin often have insulin related issues such as needle phobias, fear of hypoglycaemia, weight gain and in developing countries, costs. This Report aims at assessing insulin prescription pattern, insulin costs and issues associated with adherence. Methods: This was a Cross-sectional observation Study whereby 160 patients with DM who were on insulin solely or in combination with oral hypoglycaemic agents were recruited over a 6 month period. Information obtained from the Study subjects pertained to their histories of DM, types of insulin, insulin costs, adherence issues and insulin delivery devices. Long and short term glycaemic control were determined and evaluated for possible relation to insulin adherence. Test statistics used were chi square, t test and binary regression. Results: Insulin adherence was noted in 123-77% of the Study subjects and this was comparable between persons with type 1 DM and those with type 2 DM. The mean glycosylated haemoglobin values were significantly higher in those who admitted to non insulin