intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump a case report鞘内巴氯芬巴氯芬泵戒断综合症u2014u2014一种危及生命的并发症病例报告.pdfVIP

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intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump a case report鞘内巴氯芬巴氯芬泵戒断综合症u2014u2014一种危及生命的并发症病例报告.pdf

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intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump a case report鞘内巴氯芬巴氯芬泵戒断综合症u2014u2014一种危及生命的并发症病例报告

BMC Clinical Pharmacology BioMed Central Case report Open Access Intrathecal baclofen withdrawal syndrome- a life-threatening complication of baclofen pump: A case report 1 2 Imran Mohammed* and Asif Hussain Address: 1Department of Internal Medicine, Mercy Hospital of Pittsburgh, 1400 Locust Street, Pittsburgh, Pennsylvania 15219, United States of America and 2Department of Pharmaceutical Chemistry, Jamia Hamdard University, Hamdard Nagar, New Delhi 110062, India Email: Imran Mohammed* - doc_imran@; Asif Hussain - dr_asifhussain@ * Corresponding author Published: 09 August 2004 Received: 29 March 2004 Accepted: 09 August 2004 BMC Clinical Pharmacology 2004, 4:6 doi:10.1186/1472-6904-4-6 This article is available from: /1472-6904/4/6 © 2004 Mohammed and Hussain; licensee BioMed Central Ltd. This is an open-access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Intrathecal baclofen pump has been used effectively with increasing frequency in patients with severe spasticity, particularly for those patients who are unresponsive to conservative pharmacotherapy or develop intolerable side effects at therapeutic doses of oral baclofen. Drowsiness, nausea, headache, muscle weakness, light-headedness and return of pretreatme