miscarriage, preterm delivery, and stillbirth large variations in rates within a cohort of australian women流产、早产、死胎大在澳大利亚的女性群体的利率的变化.pdfVIP

Miscarriage, Preterm Delivery, and Stillbirth: Large Variations in Rates within a Cohort of Australian Women 1 1 2 2 1 Alexis J. Hure *, Jennifer R. Powers , Gita D. Mishra , Danielle L. Herbert , Julie E. Byles , Deborah Loxton1 1 Research Centre for Gender Health and Ageing, University of Newcastle, Callaghan, New South Wales, Australia, 2 School of Population Health, University of Queensland, Herston, Queensland, Australia Abstract Objectives: We aimed to use simple clinical questions to group women and provide their specific rates of miscarriage, preterm delivery, and stillbirth for reference. Further, our purpose was to describe who has experienced particularly low or high rates of each event. Methods: Data were collected as part of the Australian Longitudinal Study on Women’s Health, a national prospective cohort. Reproductive histories were obtained from 5806 women aged 31–36 years in 2009, who had self-reported an outcome for one or more pregnancy. Age at first birth, number of live births, smoking status, fertility problems, use of in vitro fertilisation (IVF), education and physical activity were the variables that best separated women into groups for calculating the rates of miscarriage, preterm delivery, and stillbirth. Results: Women reported 10,247 live births, 2544 miscarriages, 1113 preterm deliveries, and 113 stillbirths. Miscarriage was correlated with stillbirth (r = 0.09, P,0.001). The calculable rate of miscarriage ranged from 11.3 to 86.5 miscarriages per 100 live births. Women who had high rates of miscarriage typically had fewer live births, were more likely to smoke and were more likely to have tried unsuccessfully to conceive for $12 months. The highest