原创力文档no differences in cardiovascular autonomic responses to mental stress in chronic fatigue syndrome adolescents as compared to healthy controls没有不同的心血管自主神经反应在慢性疲劳综合症青少年精神压力与健康对照组相比.pdfVIP
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no differences in cardiovascular autonomic responses to mental stress in chronic fatigue syndrome adolescents as compared to healthy controls没有不同的心血管自主神经反应在慢性疲劳综合症青少年精神压力与健康对照组相比
Egge and Wyller BioPsychoSocial Medicine 2010, 4:22
/content/4/1/22
SHORT REPORT Open Access
No differences in cardiovascular autonomic
responses to mental stress in chronic fatigue
syndrome adolescents as compared to healthy
controls
1 2*
Caroline Egge , Vegard Bruun Wyller
Abstract
Chronic fatigue syndrome (CFS) is a disabling disease with unknown etiology. There is accumulating evidence of
altered cardiovascular autonomic responses to different somatic stressors, in particular orthostatic stress, whereas
autonomic responses to mental stress remain to be investigated. In this study, we explored cardiovascular auto-
nomic responses to a simple mental stress test in CFS patients and healthy controls.
A consecutive sample of 13 patients with CFS, aged 12 to 18 years, and a volunteer sample of 53 healthy control
subjects of equal age and gender distribution were included. Blood pressure, heart rate and acral skin blood flow
were continuously recorded during an arithmetic exercise.
At baseline, heart rate was significantly higher among CFS patients than controls (p = 0.02). During the arithmetic
exercise, however, there were no significant differences in the responses between the two groups.
In conclusion, CFS patients have unaltered autonomic responses to simple mental stress as compared to healthy
control subjects.
Chronic fatigue syndrome (CFS) is a disabling disease differences in the responses among CFS patients as
with yet unknown aetiology [1]. However, recent compared to healthy controls.
research has provided strong evidence of cardiovascular Patients with CFS aged 12 to 18 years were consecu-
autonomic disturbances during orthostatic stress [2,3], tively recruited from the outpatient
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