pharmacological effects of salvia miltiorrhiza (danshen) on cerebral infarction丹参的药理作用(丹参)在脑梗死.pdfVIP
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pharmacological effects of salvia miltiorrhiza (danshen) on cerebral infarction丹参的药理作用(丹参)在脑梗死
Lin and Hsieh Chinese Medicine 2010, 5:22
/content/5/1/22
R E V I E W Open Access
Review
Pharmacological effects of Salvia miltiorrhiza
(Danshen) on cerebral infarction
1 1,2,3
Tsai-Hui Lin and Ching-Liang Hsieh*
Abstract
Danshen, the dried root of Salvia miltiorrhiza, is a Chinese medicine used to promote blood flow and treat vascular
disease. The present article reviews the pharmacological effects of Danshen on cerebral infarction and possible
interactions between Danshen and Western drugs. Danshen may reduce or prolong the development of
atherosclerosis and may have anti-hypertensive and anti-platelet aggregation effects, which prevent cerebral
infarction. Danshen may enhance endogenous anti-oxidative enzyme activities such as the expression of endothelial
nitric oxide synthase and may scavenge oxygen free radicals. Prevention and treatment of cerebral infarction by
Danshen involves multiple pathways, including anti-atherosclerosis, anti-hypertension, anti-platelet aggregation, anti-
inflammatory and anti-oxidative effects.
Review none and dihydrotan-shinone as well as the water-soluble
Background danshensu and salvianolic acid B (Sal B) [9]. Danshen
Danshen, the dried root of Salvia miltiorrhiza, is used in inhibits platelet aggregation and promotes fibrinolysis
Chinese medicine to treat vascular disease. According to [10,11].
Chinese medicine theory, Danshen promotes blood flow Covering literature between 1990 and 2009, this article
and resolves blood stasis. Among stroke patients, 80% reviews basic and clin
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