physical activity and fat mass gain in mexican school-age children a cohort study身体活动和脂肪量增加墨西哥学龄儿童队列研究.pdf

Jáuregui et al. BMC Pediatrics 2012, 12:109 /1471-2431/12/109 RESEARCH ARTICLE Open Access Physical activity and fat mass gain in Mexican school-age children: a cohort study * Alejandra Jáuregui, Salvador Villalpando , Eduardo Rangel-Baltazar, Yaveth A Lara-Zamudio and Marcia M Castillo-García Abstract Background: In México, the prevalence of unhealthy weight increased from 24% at 6 y to 33% at 12 y of age, opening a window of opportunity to better understand the pathogenesis of obesity. The objective of this study was to explore the association between time spent on medium, vigorous physical activity (MVPA) and concurrent gains in BMI, fat mass (FM) and fat-free mass (FFM), alternately, in a cohort of Mexican children followed from kindergarten (baseline) to 2nd grade elementary school (endline). Methods: The MVPA (5-d accelerometry), BMI, FM and FFM (air displacement plethysmography) were measured at baseline and endline. Associations between gains in BMI, FM and FFM and changes in MVPA were examined using lagged and dynamic regression models, controlling for energy intake and demographic variables. Results: A total of 205 children were analyzed. Gender affected the effect of MVPA on FM gain. In girls, a high baseline MVPA predicted a lower FM gain (-0.96 kg, p=0.025) compared to low/medium MVPA. Increasing, decreasing or having a persistently high MVPA predicted a lower FM gain (range -1.6 to -1.03 kg, p0.05) compared to persistently low MVPA. In boys, increases in MVPA were associated with higher gains in BMI (+0.76 kg/m2, p=0.04) and FFM (+1.1 kg, p=0.01) compared to persistently low MVPA. Conclusion: These results support a protective role of MVPA on FM gain in girls, suggesting t