phytochemical study and anti-inflammatory, antidiabetic and free radical scavenger evaluations of krameria pauciflora methanol extract植物化学的研究和抗炎,治疗糖尿病药和自由基清除剂的评价krameria pauciflora甲醇提取.pdfVIP

phytochemical study and anti-inflammatory, antidiabetic and free radical scavenger evaluations of krameria pauciflora methanol extract植物化学的研究和抗炎,治疗糖尿病药和自由基清除剂的评价krameria pauciflora甲醇提取.pdf

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phytochemical study and anti-inflammatory, antidiabetic and free radical scavenger evaluations of krameria pauciflora methanol extract植物化学的研究和抗炎,治疗糖尿病药和自由基清除剂的评价krameria pauciflora甲醇提取

Molecules 2012, 17, 861-872; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Phytochemical Study and Anti-inflammatory, Antidiabetic and Free Radical Scavenger Evaluations of Krameria pauciflora Methanol Extract † M. Ángeles Ramírez-Cisneros 1, María Yolanda Rios 1, Myrna Déciga-Campos 2 and A. Berenice Aguilar-Guadarrama 1,* 1 Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Avenida Universidad No. 1001 Col. Chamilpa, 62209 Cuernavaca, Morelos, Mexico; E-Mails: angelesrc@uaem.mx (M.Á.R.-C.); myolanda@uaem.mx (M.Y.R.) 2 Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, México D.F., 11340, Mexico; E-Mail: mdeciga@ipn.mx † This paper is taken in part from the Ph.D. thesis of M. Ángeles Ramírez-Cisneros. * Author to whom correspondence should be addressed; E-Mail: baguilar@uaem.mx; Tel.: +52-777-329-7000 ext. 6020; Fax: +52-777-329-7998. Received: 16 December 2011; in revised form: 13 January 2012 / Accepted: 13 January 2012 / Published: 17 January 2012 Abstract: The plant Krameria pauciflora MOC et. Sessé ex DC. is used as an anti-inflammatory and antidiabetic in traditional medicine. The aim of this study was to evaluate the in vivo anti-inflammatory and antidiabetic effects of a methanol extract from the roots of K. pauciflora. Dichloromethane and ethyl acetate extracts obtained by partitioning the methanol extract were also evaluated. Compl

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