原创力文档pilot-scale production and viability analysis of freeze-dried probiotic bacteria using different protective agents半工业规模生产和可行性分析,使用不同的保护剂冻干益生菌.pdfVIP
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pilot-scale production and viability analysis of freeze-dried probiotic bacteria using different protective agents半工业规模生产和可行性分析,使用不同的保护剂冻干益生菌
Nutrients 2010, 2, 330-339; doi:10.3390/nu2030330
OPEN ACCESS
nutrients
ISSN 2072-6643
/journal/nutrients
Article
Pilot-scale Production and Viability Analysis of Freeze-Dried
Probiotic Bacteria Using Different Protective Agents
Michele Savini 1, Cinzia Cecchini 1,*, Maria Cristina Verdenelli 2, Stefania Silvi 2, Carla
2 2
Orpianesi and Alberto Cresci
1 Synbiotec S.r.l., Via d’Accorso 30/32, 62032 Camerino, Italy;
E-Mail: michele.savini@studenti.unicam.it
2 Dipartimento di Scienze Morfologiche e Biochimiche Comparate, Università di Camerino, Via
Gentile III da Varano, 62032 Camerino, Italy; E-Mails: cristina.verdenelli@unicam.it (M.C.V.);
stefania.silvi@unicam.it (S.S.); carla.orpianesi@unicam.it (C.O.); alberto.cresci@unicam.it (A.C.)
* Author to whom correspondence should be addressed; E-Mail: cinzia.cecchini@unicam.it.
Received: 23 December 2009; in revised form: 28 January 2010 / Accepted: 20 February 2010 /
Published: 11 March 2010
Abstract: The functional food industry requires an improvement of probiotic strain
stability during storage, especially when they are stored at room temperature. In this study,
the viability of freeze-dried Lactobacillus rhamnosus IMC 501® and Lactobacillus
paracasei IMC 502® using different protective agents (i.e., glycerine, mannitol, sorbitol,
inulin, dextrin, Crystalean®) was determined and compared with semi skimmed milk
(SSM) control. No significant differences were obse
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