power of qtl detection by either fixed or random models in half-sib designsqtl的检测通过固定或随机模型half-sib设计.pdfVIP

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power of qtl detection by either fixed or random models in half-sib designsqtl的检测通过固定或随机模型half-sib设计.pdf

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power of qtl detection by either fixed or random models in half-sib designsqtl的检测通过固定或随机模型half-sib设计

Genet. Sel. Evol. 37 (2005) 601–614 601 c INRA, EDP Sciences, 2005 DOI: 10.1051/gse:2005021 Original article Power of QTL detection by either ﬁxed or random models in half-sib designs a,b ∗ c Davood K , Gerald B. J , Lawrence R. S a d  , Brian O. A a Center for Genetic Improvement of Livestock, Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario N1G 2W1, Canada b Department of Animal Science, Abureihan Higher Education Complex, University of Tehran, Iran c Dekoppel Consulting, Guelph, Ontario N1G 2Y8, Canada d Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario N1G 2W1, Canada (Received 3 February 2005; accepted 16 August 2005) Abstract – The aim of this study was to compare the variance component approach for QTL linkage mapping in half-sib designs to the simple regression method. Empirical power was de- termined by Monte Carlo simulation in granddaughter designs. The factors studied (base values in parentheses) included the number of sires (5) and sons per sire (80), ratio of QTL variance