preparation and properties of the specific anti-influenza virus transfer factor准备和特定的抗流感病毒转移因子的属性.pdfVIP

Li et al. Head Face Medicine 2010, 6:22 /content/6/1/22 HEAD FACE MEDICINE METHODOLOGY Open Access Preparation and properties of the specific anti-influenza virus transfer factor * Chongbi Li , Lihua Huang, Yanping Wang, Xiangle Li, Shaowei Liang, Yingna Zheng Abstract Specific anti-influenza virus and normal transfer factors prepared in an experimental animal model, the pig, have been tested for their components, characteristics, and activity of known specificity. Two transfer factors are small molecular mixture which consist entirely or partly of polypeptides and polynucleosides. Moreover, the biological activity of transfer factors could be approved by Rosettes test and specific skin test. The study would lay a founda- tion for the research and development of other specific transfer factor. Introduction that it can be utilized for prevention, transferring immu- Transfer Factor (TF) was discovered in the 1940’s and nity prior to infection. Because it is derived from lym- has been extensively studied for the past 50 years (1). In phocytes of immune donors, it has the potential to recent years, it has been known that Transfer Factor can answer the challenge of unknown or ill-defined patho- transfer cell-mediated immunity (CMI) from an immune gens [4]. Thus, it is important that a specific TF to a donor animal to a non-immune recipient. And now it is new antigen can be made swiftly and used for preven- not only a scientifically recognized delivery system for tion as well as for the treatment of infected pat