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prevalence and risk factors of diabetes and impaired fasting glucose in nauru糖尿病、空腹血糖受损的患病率和风险因素在瑙鲁.pdf

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prevalence and risk factors of diabetes and impaired fasting glucose in nauru糖尿病、空腹血糖受损的患病率和风险因素在瑙鲁

Khambalia et al. BMC Public Health 2011, 11:719 /1471-2458/11/719 RESEARCH ARTICLE Open Access Prevalence and risk factors of diabetes and impaired fasting glucose in Nauru 1 2* 3 4 5 6 Amina Khambalia , Philayrath Phongsavan , Ben J Smith , Kieren Keke , Li Dan , Andrew Fitzhardinge and Adrian E Bauman2 Abstract Background: No comprehensive assessment of diabetes prevalence in Nauru has been conducted since an extreme prevalence was documented more than two decades ago. This study aims to determine the prevalence and risk factors of diabetes and impaired fasting glucose. Methods: A nationwide survey in 2004 of people aged 15- 64 years (n = 1592). Fasting plasma glucose levels were used to defined diabetes (≥7.0 mmol/l or 126 mg/dl) and prediabetes (6.1-6.9 mmol/l or 110-125 mg/dl). Results: The sex-standardized prevalence of diabetes was 13.0% (95% CI: 10.6, 15.4) in men, 14.4% (11.9, 16.9) in women, and 13.7% (12.0, 15.4) combined. The sex-standardized prevalence of prediabetes was 6.4% (4.6, 8.2) for men, 5.5% (3.9, 7.2) for women, and 6.0% (4.8, 7.3) combined. The prevalence of diabetes for individuals 15-24, 25-34, 35-44, 45-54 and 55-64 years was 4.5%, 7.6%, 24.1%, 32.9%, and 42.7%, respectively. The prevalence of prediabetes for the same age categories was 4.2%, 8.8%, 5.9%, 6.6%, 7.1%, respectively. Multivariable, multinomial logit modeling found risk factors for prediabetes were high cholesterol levels (OR: 2.02, 95% CI: 1.66, 2.47) and elevated waist circumference (OR: 1.04, 95% CI: 1.00, 1.08), and for diabetes were age in years (OR: 1.06; 95% CI: 1.04, 1.07), cholesterol levels (OR: 1.84, 95% CI: 1.58, 2.14) and waist circumference (OR: 1.04, 95% CI: 1.02, 1.07).