prediction of genetic merit from data on binary and quantitative variates with an application to calving difficulty, birth weight and pelvic opening预测基因的优点与应用程序二进制数据和定量变量,崩解困难,出生体重和骨盆.pdfVIP

Prediction of genetic merit from data on binary and quantitative variates with an application to calving difficulty, birth weight and pelvic opening J.L. FOULLEY, D. GIANOLA R. THOMPSON’ LN.R.A., Station de Genetique quantitative et appliquie, Centre de Recherches zootechniques, F 78350 Jouy-en-Josas Department*of Animal Science, University of Illinois, Urbana, Illinois 61801, U.S.A., A.R.C.**Unit of Statistics, University of Edinburgh, Mayfield Road, Edinburgh, EH9 3JZ, Scotland Summary A method of prediction of genetic merit from jointly distributed quanta] and quantitative responses is described. The probability of response in one of two mutually exclusive and exhaustive categories is modeled as a non-linear function of classification and« risk» variables. Inferences are made from the mode of a posterior distribution resulting from the combination of a multivariate normal density, a priori, and a product binomial likelihood function. Parameter estimates are obtained with the Newton-Raphson algorithm, which yields a system similar to the mixed model equations.« Nested» Gauss-Seidel and conjugate gradient procedures are suggested to proceed from one iterate to the next in large problems. A possible method for estimating multivariate variance (covariance) components involving, jointly, the categorical and quantitative variates is presented. The method was applied to prediction of calving difficulty as a binary variable with birth weight and pelvic opening as « risk » variables in a Blonde d’Aquitaine population. Key-words : sire evaluation, categorical data, non-linear models, prediction, Bayesian methods. Résumé Prédiction génétique à pa