原创力文档primary intravascular large b-cell lymphoma of lung a report of one case and review肺的主要血管内大b细胞淋巴瘤的案例和评审报告.pdfVIP
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primary intravascular large b-cell lymphoma of lung a report of one case and review肺的主要血管内大b细胞淋巴瘤的案例和评审报告
Yu et al. Diagnostic Pathology 2012, 7:70
/content/7/1/70
CASE REPORT Open Access
Primary Intravascular large B-cell lymphoma of
lung: a report of one case and review
1 1,2,4* 1 3
Hui Yu , Gang Chen , Rongxuan Zhang and Xiaolong Jin
Abstract
Objective: To investigate the clinicopathological features of primary intravascular large B-cell lymphoma of lung.
Methods: A case of primary pulmonary intravascular large B-cell lymphoma was analysed in histopathology and
immunophenotype.
Results: The patient is a 42-year-old female who had cough for one year. Computed tomography showed ground-
glass opacities and small nodules in bilateral lung fields. Histopathology demonstrated accumulation of similar sized
neoplastic cells within alveolar capillaries, widening the alveolar septae. The alveolar structure sustained in part of
districtions. Immunohistologically, the tumor cells were positive for CD20 and negative for CD3,CK, which were
similar to the diffuse large B-cell lymphoma.
Conclusions: Intravascular large B-cell lymphoma is an uncommon type of non-Hodgkin’s lymphoma. Primary
pulmonary presentation is even more rare. The diagnosis is based on the histopathology and
immunohistochemistry.
Virtual slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/
vs/2076991810705433.
Keywords: Intravascular large B-cell lymphoma, Primary, Lung, Clinicopathology
Background distinctly uncommon and has been rarely described. We
Intravascular large B-cell lymphoma (IVLBCL) is a rare here reported a case that manifested predominantly as
type of extranodal large B-cell lymphoma characterized
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