prodigiosin production by serratia marcescens ucp 1549 using renewable-resources as a low cost substrateprodigiosin粘质沙雷氏菌生产的跟单信用证1549使用可再生资源作为一个低成本的衬底.pdf

Molecules 2010, 15, 6931-6940; doi:10.3390/molecule OPEN ACCESS   molecules ISSN 1420-3049 /journal/molecules Article Prodigiosin Production by Serratia marcescens UCP 1549 Using Renewable-Resources as a Low Cost Substrate  Helvia W. Casullo de Araújo1,2,3, K. Fukushima 2,† and Galba M. Campos Takaki 2,* 1 Doutorado da Rede Nordeste de Biotecnologia (RENORBIO)-Universidade Católica de Pernambuco (UNICAP) Recife, PE, Brazil; E-Mail: hwcasullo@.br (H.W.C.A.) 2 Núcleo de Pesquisas em Ciências Ambientais (NPCIAMB), Universidade Católica de Pernambuco (UNICAP) 50.050-900 Recife, PE, Brazil 3 Departamento de Química, Universidade Estadual da Paraíba (UEPB), Campina Grande - PB, Brazil † Present address: Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku Chiba 260-8673, Japan. * Author to whom correspondence should be addressed; E-Mail takaki@unicap.br; Tel.: +55-81-2119.4017; Fax: +1-55-81-2119.4043. Received: 16 August 2010; in revised form: 6 September 2010 / Accepted: 9 September 2010 / Published: 8 October 2010 Abstract: A new strain of Serratia marcescens UCP1459 isolated from a semi-arid soil produced the natural red pigment prodigiosin, characterized by an uncommon pyrrolylpyrromethane skeleton. Prodigiosin is a promising drug due to its reported antifun