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prognostic factors in prostate cancer前列腺癌的预后因素
Diagnostic Pathology BioMed Central
Review Open Access
Prognostic factors in prostate cancer
1 1 3 2
A Buhmeida* , S Pyrhönen , M Laato and Y Collan
Address: 1Departments of Oncology and Radiotherapy, Turku University Hospital, Turku, Finland, 2Departments of Pathology, Turku University
Hospital, Turku, Finland and 3Departments of Surgery, Turku University Hospital, Turku, Finland
Email: A Buhmeida* - abuhme@utu.fi; S Pyrhönen - seppo.pyrhonen@tyks.fi; M Laato - matti.laato@tyks.fi; Y Collan - yrjo.collan@utu.fi
* Corresponding author
Published: 03 April 2006 Received: 20 January 2006
Accepted: 03 April 2006
Diagnostic Pathology 2006, 1:4 doi:10.1186/1746-1596-1-4
This article is available from: /content/1/1/4
© 2006 Buhmeida et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Prognostic factors in organ confined prostate cancer will reflect survival after surgical radical
prostatectomy. Gleason score, tumour volume, surgical margins and Ki-67 index have the most
significant prognosticators. Also the origins from the transitional zone, p53 status in cancer tissue,
stage, and aneuploidy have shown prognostic significance. Progressio
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