原创力文档refeeding syndrome influences outcome of anorexia nervosa patients in intensive care unit an observational study重新喂料综合症影响结果的厌食症患者在重症监护室观察研究.pdfVIP
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refeeding syndrome influences outcome of anorexia nervosa patients in intensive care unit an observational study重新喂料综合症影响结果的厌食症患者在重症监护室观察研究
Vignaud et al. Critical Care, 2010, 14:R172
/content/14/5/R172
RESEARCH Open Access
Refeeding syndrome influences outcome of
anorexia nervosa patients in intensive care unit:
an observational study
1,2 1,2* 2,3 4,2 1
Marie Vignaud , Jean-Michel Constantin , Marc Ruivard , Michele Villemeyre-Plane , Emmanuel Futier ,
Jean-Etienne Bazin 1 5 1
, Djillali Annane , for the AZUREA group (AnorexieRea Study Group)
Abstract
Introduction: Data on the epidemiology and management of anorexia nervosa (AN) in the intensive care unit
(ICU) are scarce. The aim of this study was to evaluate the prevalence and associated morbidity and mortality of
AN in French ICUs.
Methods: We randomly selected 30 ICUs throughout France. Thereafter, we retrospectively analyzed all patients
with AN admitted to any of these 30 ICUs between May 2006 and May 2008. We considered demographic data,
diagnosis at admission and complications occurring during the stay, focusing on refeeding syndrome and
management of refeeding.
Results: Eleven of the 30 ICUs participated in the retrospective study, featuring 68 patients, including 62 women.
Average body mass index at the admission was 12 ± 3 kg/m2. Twenty one were mechanically ventilated, mainly
for neurological reasons. The reported average calorie intake was 22.3 ± 13 kcal/kg/24 h. Major diagnoses at
admission were metabolic problems, refeeding survey and voluntary drug intoxication and infection. The most
common complications were metabolic, hematological, hepatic, and infectious events, of which 10% occurred
during refeeding. Seven patients developed
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