reference values for generic instruments used in routine outcome monitoring the leiden routine outcome monitoring study引用值通用仪器用于常规监测结果莱顿常规监测研究结果.pdfVIP

Schulte-van Maaren et al. BMC Psychiatry 2012, 12:203 /1471-244X/12/203 RESEARCH ARTICLE Open Access Reference values for generic instruments used in routine outcome monitoring: the leiden routine outcome monitoring study 1* 1 1 1 Yvonne WM Schulte-van Maaren , Ingrid VE Carlier , Frans G Zitman , Albert M van Hemert , Margot WM de Waal2, Martijn S van Noorden1 and Erik J Giltay1 Abstract Introduction: The Brief Symptom Inventory (BSI), Mood Anxiety Symptom Questionnaire −30 (MASQ-D30), Short Form Health Survey 36 (SF-36), and Dimensional Assessment of Personality Pathology-Short Form (DAPP-SF) are generic instruments that can be used in Routine Outcome Monitoring (ROM) of patients with common mental disorders. We aimed to generate reference values usually encountered in healthy and ‘psychiatrically ill’ populations to facilitate correct interpretation of ROM results. Methods: We included the following specific reference populations: 1294 subjects from the general population (ROM reference group) recruited through general practitioners, and 5269 psychiatric outpatients diagnosed with mood, anxiety, or somatoform (MAS) disorders (ROM patient group). The outermost 5% of observations were used to define limits for one-sided reference intervals (95th percentiles for BSI, MASQ-D30 and DAPP-SF, and 5th percentiles for SF-36 subscales). Internal consistency and Receiver Operating Characteristics (ROC) analyses were performed. Results: Mean age for the ROM reference group was 40.3 years (SD=12.6) and 37.7 years (SD=12.0) for the ROM patient group. The proportion of females was 62.8% and 64.6%, respectively. The mean for cut-off values of healthy individuals was 0.82 for the BSI subscales, 23 for the th