resistance to experimental infections with haemonchus contortus in romanov sheep抗实验性感染haemonchus contortus在罗曼诺夫羊.pdf

Original article Resistance to experimental infections with Haemonchus contortus in Romanov sheep G Luffau1J Vu Tien Khang2J Bouix2TC Nguyen P Cullen4G Ricordeau C Carrat, F Eychenne Institut National de la Recherche Agronomique; Station1de Virologie et d’Immunologie, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas; Station2d’Amédioration Génétique des Animaux, Centre de Recherches de Toulouse, BP 27, 3i326 Castanet-Tolosan Cedex; Laboratoiresdes Groupes Sanguins, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas; Laboratoire4de Génétique Biochimique, Centre de Recherches de Jouy-en-Josas, 78350 Jouy-en-Josas, France (Received 22 August 1989; accepted 28 February 1990) Summary- to immunization with human serum albumin Responses aggregated (HSA) and to repeated experimental infections with H contortus were studied in 51 female lambs of the Romanov breed, born from 8 sires and 36 dams. The 8 sires were of haemoglobin genotype Hb AB; the 51 lambs were distributed into 3 groups of 17 each, corresponding to the 3 genotypes HbAA, HbAB and HbBB. In addition the experimental lambs were typed for antigens of the major histocompatibility system (OL./1). The parasitological findings were the following: a repeatability of faecal egg counts between successive infections, a negative correlation between peak faecal egg counts and self-cure intensity, a positive correlation between faecal egg counts and degree of anaemia, a