原创力文档rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics视紫红质表达水平影响杆外节形态和光敏反应动力学.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics视紫红质表达水平影响杆外节形态和光敏反应动力学
Rhodopsin Expression Level Affects Rod Outer Segment
Morphology and Photoresponse Kinetics
1 1 1 1
Clint L. Makino *, Xiao-Hong Wen , Norman A. Michaud , Henry I. Covington ,
2 3 4 5
Emmanuele DiBenedetto , Heidi E. Hamm , Janis Lem , Giovanni Caruso
1 Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, United States of America, 2 Department of
Mathematics, Vanderbilt University, Nashville, Tennessee, United States of America, 3 Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, United
States of America, 4 Department of Ophthalmology, Program in Genetics, Program in Neuroscience, Program in Cell, Molecular and Developmental Biology, Tufts
University School of Medicine, Boston, Massachusetts, United States of America, 5 Construction Technologies Institute, National Research Council, Rome, Italy
Abstract
Background: The retinal rod outer segment is a sensory cilium that is specialized for the conversion of light into an electrical
signal. Within the cilium, up to several thousand membranous disks contain as many as a billion copies of rhodopsin for
efficient photon capture. Disks are continually turned over, requiring the daily synthesis of a prodigious amount of
rhodopsin. To promote axial diffusion in the aqueous cytoplasm, the disks have one or more incisures. Across vertebrates,
the range of disk diameters spans an order of magnitude, and the number and length of the incisures vary considerably, but
the mechanisms controlling disk architecture are not well understood. The finding that transgenic mice overexpressing
rhod
您可能关注的文档
- respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice呼吸道合胞体病毒逆转醋甲胆碱在气道高反应ovalbumin-sensitized老鼠.pdf
- respiratory support by neurally adjusted ventilatory assist (nava) in severe rsv-related bronchiolitis a case series report呼吸支持神经调整通气的协助(纳瓦)严重rsv-related细支气管炎病例分析报告.pdf
- respiratory syncytial virus persistence in macrophages alters the profile of cellular gene expression呼吸道合胞体病毒坚持巨噬细胞改变细胞基因表达的形象.pdf
- respiratory variations of inferior vena cava diameter to predict fluid responsiveness in spontaneously breathing patients with acute circulatory failure need for a cautious use呼吸变化的下腔静脉直径预测流体反应自发呼吸急性循环衰竭患者需要谨慎使用.pdf
- responder feelings in a three-player three-option ultimatum game affective determinants of rejection behavior回答者的感情在运营商3个可选最后通牒游戏情感排斥行为的决定因素.pdf
- response ant colony optimization of end milling surface roughness响应蚁群优化铣削表面粗糙度.pdf
- response inhibition impairment in high functioning autism and attention deficit hyperactivity disorder evidence from near-infrared spectroscopy data反应抑制损伤的高功能自闭症和注意缺陷多动障碍从近红外光谱数据的证据.pdf
- respiratory viral infections in children with asthma do they matter and can we prevent them儿童呼吸道病毒感染与哮喘他们物质和我们能阻止他们.pdf
- respiratory physiology and the impact of different modes of ventilation on the photoplethysmographic waveform呼吸生理的影响在photoplethysmographic波形不同的通风方式.pdf
- respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins呼吸道合胞体病毒结构组装成丝状病毒粒子粒子独立于宿主细胞骨架和相关蛋白质.pdf
- rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistancerhodacyanine导数癌细胞选择性地目标,克服了三苯氧胺耐药性.pdf
- ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snrnps核糖核蛋白装配缺陷与脊髓性肌萎缩的严重程度和优先影响的一个子集spliceosomal snrnps.pdf
- rhoe is regulated by cyclic amp and promotes fusion of human bewo choriocarcinoma cellsrhoe是由环腺苷酸,促进人类bewo绒毛膜癌的细胞的融合.pdf
- ribavirin restores esr1 gene expression and tamoxifen sensitivity in esr1 negative breast cancer cell lines利巴韦林恢复esr1基因表达和三苯氧胺敏感性esr1 -乳腺癌细胞系.pdf
- ribosomal multi-operon diversity an original perspective on the genus aeromonas核糖体multi-operon多样性原创视角属气单胞菌属.pdf
- ribonucleotide reductases of salmonella typhimurium transcriptional regulation and differential role in pathogenesis鼠伤寒沙门氏菌的核苷酸还原酶转录调控和微分在发病机制中的作用.pdf
- rice protein extracted by different methods affects cholesterol metabolism in rats due to its lower digestibility大米蛋白通过不同方法提取影响胆固醇代谢的老鼠由于其消化率低.pdf
- ribosomal protein gene knockdown causes developmental defects in zebrafish核糖体蛋白基因击倒导致斑马鱼发育缺陷.pdf
- ribozyme-mediated inhibition of 801-bp deletion-mutant epidermal growth factor receptor mrna expression in glioblastoma multiforme801 - bp deletion-mutant ribozyme-mediated抑制表皮生长因子受体信使rna表达多形性成胶质细胞瘤.pdf
- ribosome-inactivating proteins from plant defense to tumor attack从植物防御肿瘤攻击ribosome-inactivating蛋白质.pdf
文档评论（0）