schistosomes induce regulatory features in human and mouse cd1dhi b cells inhibition of allergic inflammation by il-10 and regulatory t cells在人类和小鼠血吸虫病引起的监管功能cd1dhi b细胞过敏性炎症的抑制il - 10和调节性t细胞.pdfVIP

schistosomes induce regulatory features in human and mouse cd1dhi b cells inhibition of allergic inflammation by il-10 and regulatory t cells在人类和小鼠血吸虫病引起的监管功能cd1dhi b细胞过敏性炎症的抑制il - 10和调节性t细胞.pdf

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schistosomes induce regulatory features in human and mouse cd1dhi b cells inhibition of allergic inflammation by il-10 and regulatory t cells在人类和小鼠血吸虫病引起的监管功能cd1dhi b细胞过敏性炎症的抑制il - 10和调节性t细胞

Schistosomes Induce Regulatory Features in Human and Mouse CD1dhi B Cells: Inhibition of Allergic Inflammation by IL-10 and Regulatory T Cells ¨ 1 1 1 1 Lucien E. P. M. van der Vlugt , Lucja A. Labuda , Arifa Ozir-Fazalalikhan , Ellen Lievers , Anouk K. 1,2 1 3 4 5 6 Gloudemans , Kit-Yeng Liu , Tom A. Barr , Tim Sparwasser , Louis Boon , Ulysse Ateba Ngoa , Eliane 6 1,6,7 6,7 3 1 Ngoune Feugap , Ayola A. Adegnika , Peter G. Kremsner , David Gray , Maria Yazdanbakhsh , Hermelijn H. Smits1* 1 Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands, 2 Department of Pulmonology, Erasmus Medical Center, Rotterdam, The Netherlands, 3 Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom, 4 Institute of Infection Immunology, Twincore/Centre for Experimental and Clinical Infection Research, Hanover, Germany, 5 Department of Cell Biology, Bioceros B.V., Utrecht, The ´ ´ ¨ ¨ Netherlands, 6 Medical Research Unit, Albert Schweitzer Hospital, Lambarene, Gabon, 7 Institute of Tropical Medicine, University of Tubingen, Tubingen, Germany Abstract Chronic helminth infections, such as schistosomes, are negatively associated with allergic disorders. Here, using B cell IL- 10-deficient mice, Schistosom

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