section 2. exercise-induced bronchospasm albuterol versus montelukast highlights of the asthma summit 2009 beyond the guidelines第二节。.pdfVIP

CONFERENCE PROCEEDINGS Section 2. Exercise-Induced Bronchospasm: Albuterol versus Montelukast Highlights of the Asthma Summit 2009: Beyond the Guidelines Gene Colice, MD, FCCP,1 and William J. Calhoun, MD, FACP, FCCP, FAAAAI, FACAAI2 the bronchoconstriction with EIB in asthma patients ap- Abstract: Exercise-induced bronchospasm (EIB) involves airway pears to correlate with their degree of bronchial hyperre- obstruction with an onset shortly after exercising. It can occur in 1 sponsiveness (BHR). EIB also appears in patients who do individuals without a diagnosis of asthma, but is most common in not have asthma, but nonetheless exhibit BHR. In a study asthmatic patients (and in this scenario may be referred to as of 281 nonasthmatic children, 10 (4%) experienced EIB exercise-induced asthma, EIA), correlating with the patient’s degree of airway hyperreactivity. While albuterol is the most commonly and the EIB was significantly associated with BHR to used rescue and prophylactic medication for EIB, the leukotriene histamine.2 However, neither asthma nor BHR are required for the occurrence of EIB. In members of the 1998 US antagonist, monetlukast, may be an appropriate choice for some patients. Clinical data have s