synthesis of acute phase proteins in rats with cirrhosis exposed to lipopolysaccharide急性期蛋白的合成与肝硬化大鼠暴露于脂多糖.pdfVIP
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synthesis of acute phase proteins in rats with cirrhosis exposed to lipopolysaccharide急性期蛋白的合成与肝硬化大鼠暴露于脂多糖
Comparative Hepatology BioMed Central
Research Open Access
Synthesis of acute phase proteins in rats with cirrhosis exposed to
lipopolysaccharide
1 1 2
Susanne Schouw Nielsen* , Thorbjørn Grøfte , Niels Tygstrup and
Hendrik Vilstrup1
Address: 1Department of Medicine V (Hepatology Gastroenterology), Aarhus University Hospital, Noerrebrogade 44, DK-8000 Aarhus C,
Denmark and 2Department of Medicine A, State University Hospital, 2100 Copenhagen, Denmark
Email: Susanne Schouw Nielsen* - ssnie@as.aaa.dk; Thorbjørn Grøfte - grofte@akhphd.au.dk; Niels Tygstrup - tygstrup@dadlnet.dk;
Hendrik Vilstrup - hvils@as.aaa.dk
* Corresponding author
Published: 12 September 2006 Received: 21 December 2005
Accepted: 12 September 2006
Comparative Hepatology 2006, 5:3 doi:10.1186/1476-5926-5-3
This article is available from: /content/5/1/3
© 2006 Nielsen et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: In patients with cirrhosis, infection is frequent and a leading cause of death. This is
secondary to various immunologic abnormalities in both the innate and the adaptive immune
system. However, it remains unclear whether cirrhosis affects the in
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