the effect of curcumin on human bronchial epithelial cells exposed to fine particulate matter a predictive analysis姜黄素的效果对人类支气管上皮细胞暴露于细颗粒物的预测分析.pdfVIP

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the effect of curcumin on human bronchial epithelial cells exposed to fine particulate matter a predictive analysis姜黄素的效果对人类支气管上皮细胞暴露于细颗粒物的预测分析.pdf

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the effect of curcumin on human bronchial epithelial cells exposed to fine particulate matter a predictive analysis姜黄素的效果对人类支气管上皮细胞暴露于细颗粒物的预测分析

Molecules 2012, 17, 12406-12426; doi:10.3390/molecules171012406 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article The Effect of Curcumin on Human Bronchial Epithelial Cells Exposed to Fine Particulate Matter: A Predictive Analysis Zhiguo Zhang 1,†, Xuyan Niu 2,†, Cheng Lu 2, Miao Jiang 2, Gary G. Xiao 3,* and Aiping Lu 2,4,* 1 Institute of Basic Theory, China Academy of Chinese Medical Sciences, No.16 Nanxiaojie, Dongzhimennei, Beijing 100700, China; E-Mail: zzgtcm@163.com 2 Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, No.16 Nanxiaojie, Dongzhimennei, Beijing 100700, China; E-Mails: niuxuyan@ (X.N.); lv_cheng0816@163.com (C.L.); miao_jm@ (M.J.) 3 Functional Genomics Proteomics Laboratory, Osteoporosis Research Center, Creighton University Medical Center, 601N 30th ST, Suite 6730, Omaha, NE 68131, USA 4 School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Hong Kong, China † These authors contributed equally to this work. * Authors to whom correspondence should be addressed; E-Mails: la126.com (A.L.); gxiao@ (G.G.X.); Tel.: +86-10-6406-7611 (A.L.); Fax: +86-10-8403-2881 (A.L.); Tel.: +1-402-280-5911 (G.G.X.); Fax: +1-402-280-4284 (G.G.X.). Received: 12 July 2012; in revised form: 15 October 2012 / Accepted: 16 October 2012 / Published: 22 October 2012 Abstract: Fine particulate matter (PM2.5) has been associated in humans with inflammation, oxidative stress and cancer. Studies had shown