the effect of maternal multiple micronutrient supplementation on cognition and mood during pregnancy and postpartum in indonesia a randomized trial产妇补充多种微量营养素的影响认知和情绪在怀孕期间和产后在印度尼西亚一个随机试验.pdfVIP

The Effect of Maternal Multiple Micronutrient Supplementation on Cognition and Mood during Pregnancy and Postpartum in Indonesia: A Randomized Trial 1,2,3 4 1,5 2 1,6 Elizabeth L. Prado *, Michael T. Ullman *, Husni Muadz , Katherine J. Alcock , Anuraj H. Shankar , SUMMIT Study Group 1 SUMMIT Institute of Development, Mataram, Nusa Tenggara Barat, Indonesia, 2 Psychology Department, Lancaster University, Lancaster, Lancashire, United Kingdom, 3 Program in International and Community Nutrition, University of California Davis, Davis, California, United States of America, 4 Neuroscience Department, Georgetown University, Washington, D.C., United States of America, 5 Center for Research in Language and Culture, Mataram University, Mataram, Nusa Tenggara Barat, Indonesia, 6 School of Public Health Department of Nutrition, Harvard University, Boston, Massachusetts, United States of America Abstract Maternal caregiving capacity, which is affected in part by cognition and mood, is crucial for the health of mothers and infants. Few interventions aim to improve maternal and infant health through improving such capacity. Multiple micronutrient (MMN) supplementation may improve maternal cognition and mood, since micronutrients are essential for brain function. We assessed mothers who participated in the Supplementation with Multiple Micronutrients Intervention Trial (SUMMIT), a double-blind cluster-randomized trial in Indonesia comparing MMN supplementation to iron and folic acid (IFA) during pregnancy and until three months postpartum. We adapted a set of well-studied tests of cognition, motor dexterity, and mood to the local context and administ