the efficacy of emamectin benzoate against infestations of lepeophtheirus salmonis on farmed atlantic salmon (salmo salar l) in scotland, 2002–2006的功效emamectin苯甲酸对病害lepeophtheirus salmonis在养殖的大西洋鲑鱼(大西洋鲑l)在苏格兰,2002 - 2006.pdfVIP

The Efficacy of Emamectin Benzoate against Infestations of Lepeophtheirus salmonis on Farmed Atlantic Salmon (Salmo salar L) in Scotland, 2002–2006 1,2 2 1 2 Fiona Lees , Mark Baillie , George Gettinby , Crawford W. Revie * 1 Department of Statistics and Modelling Science, University of Strathclyde, Glasgow, United Kingdom, 2 Department of Computer and Information Sciences, University of Strathclyde, Glasgow, United Kingdom Abstract Background: Infestations of the parasitic copepod Lepeophtheirus salmonis, commonly referred to as sea lice, represent a major challenge to commercial salmon aquaculture. Dependence on a limited number of theraputants to control such infestations has led to concerns of reduced sensitivity in some sea lice populations. This study investigates trends in the efficacy of the in-feed treatment emamectin benzoate in Scotland, the active ingredient most widely used across all salmon producing regions. Methodology/Principal Findings: Study data were drawn from over 50 commercial Atlantic salmon farms on the west coast of Scotland between 2002 and 2006. An epi-informatics approach was adopted whereby available farm records, descriptive epidemiological summaries and statistical linear modelling methods were used to identify factors that significantly affect sea lice abundance following treatment with emamectin benzoate (SLICEH, Schering Plough Animal Health). The results show that although sea lice infestations are reduced following the application of emamectin benzoate, not all treatments are effective. Specifically there is evidence of variation across geographical regions and a reduction in efficacy over time. Conclusions/Significance: Reduced sensitivity and potential resistance to currently available medicines are constant t