the esophagus not just for food anymore食道不仅对食物了.pdfVIP

Zaccheo et al. Critical Care 2010, 14:326 /content/14/6/326 J O U R N A L C LU B C R I T I Q U E The esophagus … not just for food anymore? 1 2 3 Matthew Zaccheo , Eric B Milbrandt , and Arthur Boujoukos* University of Pittsburgh Department of Critical Care Medicine: Evidence-Based Medicine Journal Club, edited by Sachin Yende Expanded Abstract Syndrome Network standard-of-care recommendations Citation (the control group). Talmor D, Sarge T, Malhotra A, O’Donnell CR, Ritz R, Outcomes: h e primary end point was improvement in Lisbon A, Novack V, Loring SH: Mechanical ventilation oxygenation at 72 hours after randomization. Secondary guided by esophageal pressure in acute lung injury. N end points included indexes of lung mechanics and gas Engl J Med 2008, 359:2095-2104 [1]. exchange, number of ventilator free days, length of ICU stay, and death at 28 days and 180 days. Background Survival of patients with acute lung injury or the acute Results respiratory distress syndrome (ARDS) has been improved h e study reached its stopping criterion and was by ventilation with small tidal volumes and the use of terminated after 61 patients had been enrolled. h e ratio positive end-expiratory pressure (PEEP); the optimal of the partial pressure of arterial oxygen to the fraction of level of PEEP has been difficult to determine. In this pilot inspired oxygen at 72 hours was 88 mmHg higher in