原创力文档the expression of vegf-a is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosisvegf-a下降的表达调节外周血单核细胞的继发性进展型多发性硬化症患者.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
the expression of vegf-a is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosisvegf-a下降的表达调节外周血单核细胞的继发性进展型多发性硬化症患者
The Expression of VEGF-A Is Down Regulated in
Peripheral Blood Mononuclear Cells of Patients with
Secondary Progressive Multiple Sclerosis
1 2. ¨ 1. 1 1 3
Ellen Iacobaeus *, Petra Amoudruz , Mikael Strom , Mohsen Khademi , Lou Brundin , Jan Hillert ,
1 ¨ 2 1 4 1
Ingrid Kockum , Vivianne Malmstrom , Tomas Olsson , Emma Tham , Fredrik Piehl
1 Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden, 2 Department of Medicine,
Rheumatology Unit, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden, 3 Department of Clinical Neuroscience, The Multiple Sclerosis Research
Group, Karolinska Institute Solna, Center for Molecular Medicine, Stockholm, Sweden, 4 Department of Clinical Genetics, L5:03, Karolinska University Hospital, Solna,
Sweden
Abstract
Background: Most patients with relapsing-remitting multiple sclerosis (RRMS) eventually enter a secondary progressive
(SPMS) phase, characterized by increasing neurological disability. The mechanisms underlying transition to SPMS are
unknown and effective treatments and biomarkers are lacking. Vascular endothelial growth factor-A (VEGF-A) is an
angiogenic factor with neuroprotective effects that has been associated with neurodegenerative diseases. SPMS has a
prominent neurodegenerative facet and we investigated a possible role for VEGF-A during transition from RRMS to SPMS.
Methodology/Principal Findings: VEGF-A mRNA expre
您可能关注的文档
- the economic and social benefits and the barriers of providing people with disabilities accessible clean water and sanitation经济效益和社会效益和壁垒提供残疾人使用的洁净水和卫生设施.pdf
- the economic burden of treating neonates in intensive care units (icus) in greece的经济负担治疗新生儿重症监护病房(icu)在希腊.pdf
- the economic cost of unsupplied diesel product in korea using input-output analysisunsupplied柴油产品的经济成本在韩国使用投入产出分析.pdf
- the economic impact of chronic fatigue syndrome慢性疲劳综合症的经济影响.pdf
- the economic impact of chronic fatigue syndrome in georgia direct and indirect costs在格鲁吉亚的经济影响慢性疲劳综合症的直接和间接成本.pdf
- the economic impact of non-communicable diseases on households in india非传染性疾病对家庭的经济影响在印度.pdf
- the dynamics of people movement systems in central areas在中部地区人们运动的动力学系统.pdf
- the economics of health and climate change key evidence for decision making健康和气候变化的经济决策的关键证据.pdf
- the economics of primary prevention of cardiovascular disease – a systematic review of economic evaluations心血管疾病的一级预防的经济学u2014u2014经济评估的系统回顾.pdf
- the economic value of mangroves a meta-analysis红树林的经济价值分析.pdf
- the expression of small regulatory rnas in clinical samples reflects the different life styles of staphylococcus aureus in colonization vs. infection小监管rna的表达在临床样本反映出不同的生活风格殖民与金黄色葡萄球菌的感染.pdf
- the expression profiling of the lipoxygenase (lox) family genes during fruit development, abiotic stress and hormonal treatments in cucumber (cucumis sativus l.)表达式分析脂氧合酶(lox)家族基因在水果的发展过程中,非生物压力和荷尔蒙治疗黄瓜(cucumis巨大).pdf
- the expression signature of in vitro senescence resembles mouse but not human aging体外衰老的表情特征类似于老鼠但不是人类衰老.pdf
- the extended functional neuroanatomy of emotional processing biases for masked faces in major depressive disorder扩展功能的神经解剖学的情感处理偏见掩盖了在重度抑郁症.pdf
- the extension of statistical entropy analysis to chemical compounds扩展的统计熵分析化合物.pdf
- the extent of the psychological impairment of prosthodontic outpatients at a german university hospital口腔门诊病人的心理障碍的程度在一个德国大学医院.pdf
- the extended cleavage specificity of human thrombin扩展的乳沟人类凝血酶的特异性.pdf
- the expression of mtus1atip and its major isoforms, atip1 and atip3, in human prostate cancermtus1atip及其主要亚型的表达,atip1 atip3,在人类前列腺癌.pdf
- the extinction of the conulariidsconulariids的灭绝.pdf
- the extracytoplasmic domain of the mycobacterium tuberculosis serthr kinase pknb binds specific muropeptides and is required for pknb localization结核分枝杆菌的extracytoplasmic域serthr激酶pknb pknb需要结合具体muropeptides和本地化.pdf
文档评论（0）