the impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability脓毒症的严重程度的影响在低血糖的风险和血糖的变化.pdfVIP

Available online /content/12/5/R129 Vol 12 No 5 Open Access Research The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variability 1 1 2 1 1 Reiner M Waeschle , Onnen Moerer , Reinhard Hilgers , Peter Herrmann , Peter Neumann and Michael Quintel1 1Department of Anaesthesiology, Emergency and Intensive Care Medicine, University of Goettingen, Robert-Koch-Strasse 40, Goettingen, 37075, Germany 2Department of Medical Statistics, University of Goettingen, Humboldtallee 32, Goettingen, 37073, Germany Corresponding author: Reiner M Waeschle, rwaeschle@gmx.de Received: 25 Apr 2008 Revisions requested: 15 Jun 2008 Revisions received: 11 Sep 2008 Accepted: 21 Oct 2008 Published: 21 Oct 2008 Critical Care 2008, 12:R129 (doi:10.1186/cc7097) This article is online at: /content/12/5/R129 © 2008 Waeschle et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction The purpose of this study was to assess the 73.5%, septic shock: 88.5%, p = 0.0005; 240 mg/dl: sepsis: relation between glycaemic control and the severity of sepsis in 17.0%, severe sepsis: 48.2%, septic shock: 45.9%, p = a cohort of patients treated with intensive insulin therapy (IIT). 0.0011). Multivariate analyses showed a significant association