ultrasound-assisted extraction of syringin from the bark of ilex rotunda thumb using response surface methodologyultrasound-assisted提取syringin冬青属植物树皮的圆形大厅拇指使用响应面方法.pdfVIP
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ultrasound-assisted extraction of syringin from the bark of ilex rotunda thumb using response surface methodologyultrasound-assisted提取syringin冬青属植物树皮的圆形大厅拇指使用响应面方法
Int. J. Mol. Sci. 2012, 13, 7607-7616; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Communication
Ultrasound-Assisted Extraction of Syringin from the Bark of
Ilex rotunda Thumb Using Response Surface Methodology
Li-Chun Zhao 1,2, Ying He 2, Xin Deng 2, Xiang-Hua Xia 1, Jian Liang 2, Geng-Liang Yang 1,*,
Wei Li 3 and Hui Wang 4,*
1 College of Pharmacy, Hebei University, Baoding 071002, China;
E-Mails: hyzlc@126.com (L.-C.Z.); xhxiagx@126.com (X.-H.X.)
2 The Affiliated Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning 530011, China;
E-Mails: hyinggx@ (Y.H.); dx2000@ 126.com (X.D.); ljruikang@126.com (J.L.)
3 College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China;
E-Mail: liwei7727@126.com
4 China-Japan Union Hospital, Jilin University, Changchun 130033, China
* Authors to whom correspondence should be addressed; E-Mails: ygl@ (G.-L.Y.);
hwangjlu@126.com (H.W.); Tel.: +86-312-5971107 (G.-L.Y.); +86-431(H.W.).
Received: 28 April 2012; in revised form: 12 May 2012 / Accepted: 15 May 2012 /
Published: 20 June 2012
Abstract: In this work, a rapid extraction method based on ultrasound-assisted extraction
(UAE) of syringin from the bark of Ilex rotunda Thumb using response surface
methodology (RSM) is described. The syringin was analyzed and quantified by high
performance liquid chromatography coupled with UV detection (HPLC-UV). The
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