原创力文档crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor晶体结构的两个氨基糖苷类激酶绑定与真核蛋白激酶抑制剂.pdfVIP
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crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor晶体结构的两个氨基糖苷类激酶绑定与真核蛋白激酶抑制剂
Crystal Structures of Two Aminoglycoside Kinases Bound
with a Eukaryotic Protein Kinase Inhibitor
Desiree H. Fong1,2., Bing Xiong3.¤a, Jiyoung Hwang1¤b, Albert M. Berghuis1,2,3*
1 Department of Biochemistry, McGill University, Montreal, Quebec, Canada, 2 Groupe de Recherche GRASP, McGill University, Montreal, Quebec, Canada, 3 Department
of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada
Abstract
Antibiotic resistance is recognized as a growing healthcare problem. To address this issue, one strategy is to thwart the
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