determinants of initiation codon selection during translation in mammalian cells起始密码子选择的决定因素在翻译在哺乳动物细胞.pdfVIP

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determinants of initiation codon selection during translation in mammalian cells起始密码子选择的决定因素在翻译在哺乳动物细胞.pdf

determinants of initiation codon selection during translation in mammalian cells起始密码子选择的决定因素在翻译在哺乳动物细胞

Determinants of Initiation Codon Selection during Translation in Mammalian Cells Daiki Matsuda, Vincent P. Mauro* Department of Neurobiology, The Scripps Research Institute and The Skaggs Institute for Chemical Biology, La Jolla, California, United States of America Abstract Factors affecting translation of mRNA contribute to the complexity of eukaryotic proteomes. In some cases, translation of a particular mRNA can generate multiple proteins. However, the factors that determine whether ribosomes initiate translation from the first AUG codon in the transcript, from

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