developing and applying heterogeneous phylogenetic models with xrate开发和应用与xrate异构系统模型.pdfVIP

Developing and Applying Heterogeneous Phylogenetic Models with XRate Oscar Westesson, Ian Holmes* Department of Bioengineering, University of California, Berkeley, California, United States of America Abstract Modeling sequence evolution on phylogenetic trees is a useful technique in computational biology. Especially powerful are models which take account of the heterogeneous nature of sequence evolution according to the ‘‘grammar’’ of the encoded gene features. However, beyond a modest level of model complexity,