differential modulation of tcflef-1 activity by the soluble lrp6-icd由可溶性lrp6-icd微分tcflef-1活动的调制.pdfVIP

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differential modulation of tcflef-1 activity by the soluble lrp6-icd由可溶性lrp6-icd微分tcflef-1活动的调制.pdf

differential modulation of tcflef-1 activity by the soluble lrp6-icd由可溶性lrp6-icd微分tcflef-1活动的调制

Differential Modulation of TCF/LEF-1 Activity by the Soluble LRP6-ICD Brandon Beagle1,2, Gail V. W. Johnson1,2* 1 Departments of Anesthesiology and Pharmacology and Physiology, University of Rochester, Rochester, New York, United States of America, 2 Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America Abstract The canonical Wnt/ b-catenin (Wnt) pathway is a master transcriptional regulatory signaling pathway that controls numerous biological processes including proliferation and differentiation

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