differentiating embryonic stem cells pass through ‘temporal windows’ that mark responsiveness to exogenous and paracrine mesendoderm inducing signals区分胚胎干细胞通过u201c时间窗口u201d,马克响应能力外生和旁分泌mesendoderm诱导信号.pdfVIP

Differentiating Embryonic Stem Cells Pass through ‘Temporal Windows’ That Mark Responsiveness to Exogenous and Paracrine Mesendoderm Inducing Signals Steven A. Jackson¤a¤b, Jacqueline Schiesser, Edouard G. Stanley., Andrew G. Elefanty*. Monash Immunology and Stem Cell Laboratories, Monash University, Clayton, Victoria, Australia Abstract Background: Mesendoderm induction during embryonic stem cell (ESC) differentiation in vitro is stimulated by the Transforming Growth Factor and Wingless (Wnt) families of growth factors. Prin