dissociating markers of senescence and protective ability in memory t cells分离的标记在内存中t细胞衰老和防护能力.pdfVIP

Dissociating Markers of Senescence and Protective Ability in Memory T Cells Martin Prlic*¤a, Jilian A. Sacks¤b, Michael J. Bevan* Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America Abstract No unique transcription factor or biomarker has been identified to reliably distinguish effector from memory T cells. Instead a set of surface markers including IL-7Ra and KLRG1 is commonly used to predict the potential of CD8 effector T cells to differentiate