disturbed relaxin signaling pathway and testicular dysfunction in mouse offspring upon maternal exposure to simazine打扰耻骨松弛激素信号通路和睾丸功能障碍在老鼠的后代产妇接触西玛津.pdfVIP

Disturbed Relaxin Signaling Pathway and Testicular Dysfunction in Mouse Offspring upon Maternal Exposure to Simazine Ho-Oak Park, Jeehyeon Bae* College of Pharmacy, Chung-Ang University, Seoul, Korea Abstract Simazine is a triazine herbicide that is being widely applied worldwide and commonly detected in surface and groundwater. Despite its popular use in controlling weeds and algae, very limited information is available regarding its toxicity. In the present study, pregnant mice were orally exposed to low doses (0, 5, 50, or 500 mg/kg body weight per day) of simazi