efficient feeder-free episomal reprogramming with small molecules高效feeder-free游离与小分子重组.pdfVIP
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efficient feeder-free episomal reprogramming with small molecules高效feeder-free游离与小分子重组
Efficient Feeder-Free Episomal Reprogramming with
Small Molecules
Junying Yu*, Kevin Fongching Chau, Maxim A. Vodyanik, Jinlan Jiang, Yong Jiang
Advanced Development Programs, Cellular Dynamics International, Inc., Madison, Wisconsin, United States of America
Abstract
Genetic reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) could offer replenishable cell
sources for transplantation therapies. To fulfill their promises, human iPSCs will ideally be free of exogenous DNA (footprint-
free), and be derived and cultured in
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