enzyme activity in the crowded milieu酶活性在拥挤的环境.pdfVIP

Enzyme Activity in the Crowded Milieu ¨ Tobias Vopel, George I. Makhatadze* Department of Biology and Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, United States of America Abstract The cytosol of a cell is a concentrated milieu of a variety of different molecules, including small molecules (salts and metabolites) and macromolecules such as nucleic acids, polysaccharides, proteins and large macromolecular complexes. Macromolecular crowding in the cytosolic env