部分药理学笔记（Partial pharmacological notes）.docVIP

部分药理学笔记（Partial pharmacological notes） Anticholinergic agents M cholinergic receptor blocking agent, P43 * atropine [function] competitive blocking M-R (non selective M1-M5), large dose of blocking N-R 1, gland: inhibition of the secretion of the salivary glands, sweat glands, the most sensitive, 2 eyes: Atropine mydriatic iris sphincter M cholinergic receptor, the mydriasis. Elevated intraocular pressure: real water and reflux adjusting paralysis: ciliary muscle relaxation back to the outer edge of the suspensory ligament tension, the lens is flat, only to see distant objects, not nearly were clearly imaged on the retina, see near objects blurred, namely control paralysis. 3, the relaxation of smooth muscle on the gastrointestinal smooth muscle: inhibition of gastrointestinal smooth spasm, reduce peristalsis amplitude and frequency, alleviate gastrointestinal colic. The urethral smooth muscle and bladder detrusor have relaxation of the biliary tract, ureter, uterus and bronchial smooth muscle relaxation effect is weak, 4 cardiovascular system: heart excited, the expansion of the small blood vessels (vascular and blood pressure: large dose of skin expansion of blood vessels, *) [1.]: clinical application of visceral colic relieving spasm of smooth muscle (the effect of gastrointestinal smooth muscle bladder irritation) 2. glands secrete too much: (1) for general anesthesia administration (2) for severe night sweats and ptyalism in 3. eye (1) iridocyclitis (2) retinal fundus (i.e. check) (3) optometry glasses (limited to children) 4. slow arrhythmia in 5. septic shock 6. organophosphate poisoning [taboo] hypertrophy of the prostate, glaucoma disabled. (urethral sphincter contraction, detrusor relaxation, dysuria) Anisodamine (familiar). [Characteristics] 1, not easily through the blood-brain barrier, central excitatory role is small; 2, relieve gastrointestinal smooth muscle spasm and vasospasm obvious; 3, mydriasis effect and inhibition of gland secretion as atropin