抗中性粒细胞胞浆抗体在风湿性疾病中的作用（The role of antineutrophil cytoplasmic antibodies in rheumatic diseases）.docVIP

抗中性粒细胞胞浆抗体在风湿性疾病中的作用（The role of antineutrophil cytoplasmic antibodies in rheumatic diseases） The role of antineutrophil cytoplasmic antibodies in rheumatic diseases Update Date: 08-27, Zhang Wen, Ceng Xiaofeng I. The history of antineutrophil cytoplasmic antibodies (ANCA) Antineutrophil cytoplasmic antibodies are a heterogeneous group of autoantibodies targeting the cytoplasmic target antigens of neutrophils and monocytes. In 1982, Davies et al reported the presence of an anti neutrophil cytoplasmic IgG antibody in sera of 8 patients with segmental necrotizing glomerulonephritis. At that time